Description

Carbamic Acid, [3-(Aminomethyl)Cyclopentyl]-, 1,1-Dimethylethyl Ester is a high-purity, protected amino acid derivative of significant interest in advanced organic synthesis. This compound matters as a critical chiral building block for the construction of complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by medicinal chemists and process development scientists for the synthesis of novel active pharmaceutical ingredients (APIs), peptide mimetics, and other bioactive compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents, including central nervous system (CNS) drugs and enzyme inhibitors.
• Peptidomimetic Synthesis: Serves as a constrained, cyclopentyl-based scaffold for creating non-peptide compounds that mimic peptide structure and function.
• Protecting Group Strategy: The 1,1-dimethylethyl (tert-butyloxycarbonyl, Boc) group provides orthogonal protection for the amine functionality in multi-step synthetic sequences.
• Chemical Biology Probes: Used in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Asymmetric Catalysis Ligand Precursor: Potential precursor for chiral ligands used in asymmetric hydrogenation and other enantioselective transformations.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global pharmaceutical industry.

Basic Information

Product Name	Carbamic Acid, [3-(Aminomethyl)Cyclopentyl]-, 1,1-Dimethylethyl Ester
CAS No.	1523617-91-5
Molecular Formula	C11H21NO2
Molecular Weight	199.29 g/mol
Synonyms	(1,1-Dimethylethyl) N-[(3-aminomethyl)cyclopentyl]carbamate; tert-Butyl N-[(3-aminomethyl)cyclopentyl]carbamate; Boc-3-(Aminomethyl)cyclopentylamine; N-Boc-3-(Aminomethyl)cyclopentylamine; (3-Aminomethylcyclopentyl)carbamic acid tert-butyl ester; 1,1-Dimethylethyl [3-(aminomethyl)cyclopentyl]carbamate; tert-Butyl (3-(aminomethyl)cyclopentyl)carbamate
EINECS	Contact for details

Quality Control

Our Carbamic Acid, [3-(Aminomethyl)Cyclopentyl]-, 1,1-Dimethylethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the exacting standards required for pharmaceutical R&D and scale-up. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.