Description

(2R,11Br)-4-Hydroxy-2,6-Bis(2,4,6-Tricyclohexylphenyl)Dinaphtho[2,1-D:1',2'-F][1,3,2]Dioxaphosphepine 4-Oxide is a sophisticated, chiral organophosphorus compound characterized by its sterically demanding dinaphthodioxaphosphepine core. This compound matters as a highly effective chiral ligand or catalyst precursor in asymmetric synthesis, enabling the production of enantiomerically pure pharmaceuticals and fine chemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for developing novel synthetic routes.

Application

• Asymmetric Catalysis: Serving as a privileged chiral ligand for transition metal-catalyzed reactions such as hydrogenation, hydroformylation, and cross-coupling.
• Pharmaceutical Intermediate Synthesis: Enabling the asymmetric synthesis of key chiral building blocks for active pharmaceutical ingredients (APIs).
• Agrochemical Research: Facilitating the development of enantioselective pathways for novel herbicides, fungicides, and insecticides.
• Material Science: Potential use in the synthesis of chiral polymers or as a component in advanced catalytic systems for specialty chemicals.
• Academic & Industrial R&D: A valuable tool for methodological development in organic synthesis and catalysis research.
• Process Chemistry Optimization: Used to improve the enantioselectivity and yield of established manufacturing processes for fine chemicals.

Basic Information

Product Name	(2R,11Br)-4-Hydroxy-2,6-Bis(2,4,6-Tricyclohexylphenyl)Dinaphtho[2,1-D:1',2'-F][1,3,2]Dioxaphosphepine 4-Oxide
CAS No.	1522367-59-4
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	(2R,11Br)-4-Hydroxy-2,6-bis(2,4,6-tricyclohexylphenyl)dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepine 4-oxide; Chiral BINOL-derived phosphine oxide ligand; Sterically hindered phosphine oxide; Asymmetric catalysis ligand CAS 1522367-59-4; Dinaphthodioxaphosphepine ligand; P-Chiral ligand; (R)-BINOL-based phosphine oxide.
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized using advanced analytical techniques to confirm identity, chiral purity, and chemical purity. Certificates of Analysis (COA) detailing specifications such as enantiomeric excess (ee) and assay are available upon request. We adhere to strict internal quality protocols to ensure reliable batch-to-batch consistency for your research and development needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Keep the container sealed under an inert atmosphere if the material is sensitive to oxidation. Handle and store in accordance with good laboratory practices.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥95%
Enantiomeric Excess (Chiral HPLC)	≥99% ee
Melting Point	Contact for details
Specific Rotation	Contact for details
Heavy Metals	<10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.