Description

5-Iodo-1-Methyl-1H-Pyrazole-4-Carbonitrile is a versatile and highly functionalized heterocyclic building block. Its value lies in its unique molecular architecture, which incorporates an iodine atom and a nitrile group on a pyrazole core, making it a critical intermediate for constructing complex molecules. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for advanced synthesis and medicinal chemistry applications.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting various disease pathways.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its halogenated heterocyclic structure.
• Material Science Research: Acts as a building block for creating specialized polymers, ligands, or organic electronic materials due to its functional groups.
• Medicinal Chemistry & Drug Discovery: Employed in high-throughput screening and structure-activity relationship (SAR) studies to explore new chemical entities.
• Cross-Coupling Reactions: The iodine substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to create complex biaryl systems.
• Chemical Biology Probes: Utilized in the development of molecular probes and tags for studying biological processes.

Basic Information

Product Name	5-Iodo-1-Methyl-1H-Pyrazole-4-Carbonitrile
CAS No.	1516303-92-6
Molecular Formula	C5H4IN3
Molecular Weight	233.01 g/mol
Synonyms	1-Methyl-5-iodo-1H-pyrazole-4-carbonitrile; 5-Iodo-1-methyl-1H-pyrazole-4-carbonitrile; 4-Cyano-5-iodo-1-methylpyrazole; 1-Methyl-5-iodopyrazole-4-carbonitrile; 1516303-92-6; 5-Iodo-1-methylpyrazole-4-carbonitrile
EINECS	Contact for details

Quality Control

Our 5-Iodo-1-Methyl-1H-Pyrazole-4-Carbonitrile is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). This material is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.