Description

(1-Cyclobutyl-2,2,2-trifluoroethyl)(methyl)amine is a specialized fluorinated amine building block of significant interest in modern synthetic chemistry. Its core value lies in the unique combination of a cyclobutyl ring and a trifluoroethylamine moiety, which can impart desirable properties like metabolic stability and altered lipophilicity to target molecules. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly those targeting central nervous system (CNS) disorders, where the fluorinated cyclobutyl group can enhance blood-brain barrier penetration and metabolic stability.
• Agrochemical Synthesis: Used in creating advanced intermediates for novel herbicides, fungicides, and insecticides, where the fluorine atoms can increase biological activity and environmental persistence.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands or catalysts in asymmetric synthesis, leveraging the amine functionality for metal coordination.
• Material Science Research: Employed in the development of specialty polymers and advanced materials, where fluorinated amines can modify surface properties and chemical resistance.
• Fluorine Chemistry Building Block: An essential reagent for introducing the 1-cyclobutyl-2,2,2-trifluoroethylamine motif into more complex molecular architectures during exploratory chemistry.

Basic Information

Product Name	(1-Cyclobutyl-2,2,2-trifluoroethyl)(methyl)amine
CAS No.	1513411-07-8
Molecular Formula	C7H12F3N
Molecular Weight	167.17 g/mol
Synonyms	N-Methyl-1-(cyclobutyl)-2,2,2-trifluoroethanamine; 1-Cyclobutyl-2,2,2-trifluoro-N-methylethanamine; N-Methyl-2,2,2-trifluoro-1-cyclobutylethanamine; Methyl(1-cyclobutyl-2,2,2-trifluoroethyl)amine; 2,2,2-Trifluoro-1-cyclobutylethyl(methyl)amine; 1-(Cyclobutyl)-2,2,2-trifluoroethylmethylamine
EINECS	Contact for details

Quality Control

Our production of (1-Cyclobutyl-2,2,2-trifluoroethyl)(methyl)amine adheres to stringent internal quality protocols to ensure batch-to-batch consistency and high purity for research and development applications. Quality is verified through advanced analytical techniques including GC, HPLC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its amine functionality and light-sensitive nature, prolonged exposure to light or air should be avoided.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Purity (HPLC)	≥ 96.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.