Description

2-Cyanocyclobutane-1-Carboxylic Acid is a versatile and high-value bifunctional building block in advanced organic synthesis. Its unique strained cyclobutane ring system, combined with both carboxylic acid and nitrile functional groups, makes it a critical intermediate for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially those containing constrained ring systems for improved metabolic stability and target binding.
• Agrochemical Synthesis: Building block for creating advanced herbicides, fungicides, and insecticides with unique modes of action.
• Material Science Research: Used in the development of specialty polymers and functional materials with tailored properties.
• Chemical Biology Probes: Serves as a scaffold for creating molecular probes and tools to study biological pathways.
• Peptidomimetics: Enables the incorporation of rigid, non-natural amino acid analogs into peptide chains for drug discovery.
• Catalyst Ligand Development: Useful for synthesizing novel chiral ligands used in asymmetric catalysis.

Basic Information

Product Name	2-Cyanocyclobutane-1-Carboxylic Acid
CAS No.	1508446-57-8
Molecular Formula	C6H7NO2
Molecular Weight	125.13 g/mol
Synonyms	Cyclobutane-1-carboxylic acid, 2-cyano-; 2-Cyanocyclobutanecarboxylic Acid; 1-Carboxy-2-cyanocyclobutane; 2-Cyano-1-cyclobutanecarboxylic Acid; (1R,2S)-rel-2-Cyanocyclobutanecarboxylic Acid (for stereoisomers); 2-CN-Cyclobutane-1-COOH
EINECS	Contact for details

Quality Control

Every batch of 2-Cyanocyclobutane-1-Carboxylic Acid is manufactured under strict quality management systems. We provide comprehensive analytical documentation to ensure product integrity and traceability for your regulatory filings. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.