Description

tert-Butyl (5-Hydroxypiperidin-3-Yl)Carbamate is a high-purity, protected piperidine derivative of significant interest in advanced organic synthesis. This compound serves as a versatile and critical building block for the development of novel pharmaceutical agents and bioactive molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry, process development, and the synthesis of complex heterocyclic targets.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly those targeting the central nervous system (CNS) and other therapeutic areas.
• Medicinal Chemistry Building Block: Used for the construction of complex molecular scaffolds, enabling structure-activity relationship (SAR) studies and lead optimization.
• Process Chemistry: Employed in route scouting and scale-up synthesis for Active Pharmaceutical Ingredients (APIs) requiring functionalized piperidine cores.
• Protecting Group Strategy: The tert-butyloxycarbonyl (Boc) group allows for selective protection of the amine functionality during multi-step synthetic sequences.
• Chemical Biology Research: Useful in the synthesis of molecular probes and tool compounds for studying biological pathways and protein interactions.
• Custom Synthesis: Serves as a starting material for contract research and manufacturing organizations (CROs/CMOs) producing specialized fine chemicals for clients.

Basic Information

Product Name	tert-Butyl (5-Hydroxypiperidin-3-Yl)Carbamate
CAS No.	1502766-14-4
Molecular Formula	C10H20N2O3
Molecular Weight	216.28 g/mol
Synonyms	tert-Butyl 5-hydroxypiperidin-3-ylcarbamate; 3-[[(1,1-Dimethylethoxy)carbonyl]amino]-5-hydroxypiperidine; 5-Hydroxy-3-piperidinecarboxylic acid 1,1-dimethylethyl ester; 3-(Boc-amino)-5-hydroxypiperidine; (5-Hydroxypiperidin-3-yl)carbamic acid tert-butyl ester; N-Boc-3-amino-5-hydroxypiperidine; tert-Butyl N-(5-hydroxypiperidin-3-yl)carbamate
EINECS	Contact for details

Quality Control

Our tert-Butyl (5-Hydroxypiperidin-3-Yl)Carbamate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and supporting regulatory filings for research and development purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.