Description

(Z)-Methyl 3-((2'-(N'-Hydroxycarbamimidoyl)Biphenyl-4-Yl)Methyl)-2-Oxo-2,3-Dihydro-1H-Benzo[D]Imidazole-4-Carboxylate CAS NO 1499167-72-4 is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant value in medicinal chemistry research and development, particularly for its role as a key building block in the synthesis of novel therapeutic agents. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of small molecule drugs targeting various disease pathways.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting enzyme inhibition.
• Medicinal Chemistry Research: Used as a core scaffold or building block for structure-activity relationship (SAR) studies and lead optimization.
• Protease Inhibitor Development: Its structural features make it relevant for research into inhibitors for various protease targets.
• Chemical Biology Probes: Serves as a starting material for creating labeled or modified compounds used to study biological processes.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for exploratory synthetic chemistry and pharmacology projects.

Basic Information

Product Name	(Z)-Methyl 3-((2'-(N'-Hydroxycarbamimidoyl)Biphenyl-4-Yl)Methyl)-2-Oxo-2,3-Dihydro-1H-Benzo[D]Imidazole-4-Carboxylate
CAS No.	1499167-72-4
Molecular Formula	C25H22N4O4
Molecular Weight	442.47 g/mol
Synonyms	Methyl (Z)-3-{[2'-(N-hydroxycarbamimidoyl)biphenyl-4-yl]methyl}-2-oxo-2,3-dihydro-1H-benzimidazole-4-carboxylate; (Z)-Methyl 3-((2'-(N-Hydroxycarbamimidoyl)-[1,1'-biphenyl]-4-yl)methyl)-2-oxo-2,3-dihydro-1H-benzo[d]imidazole-4-carboxylate; 1499167-72-4; Biphenyl benzimidazole derivative; Hydroxyamidine intermediate; CAS 1499167-72-4
EINECS	Contact for details

Quality Control

Our (Z)-Methyl 3-((2'-(N'-Hydroxycarbamimidoyl)Biphenyl-4-Yl)Methyl)-2-Oxo-2,3-Dihydro-1H-Benzo[D]Imidazole-4-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS), to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and analytical results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a dry environment and protected from light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.