Description

5-Fluoro-2-Isopropoxyphenylboronic Acid Pinacol Ester is a high-purity, protected boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of active pharmaceutical ingredients (APIs), agrochemicals, and advanced organic materials.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds between aryl halides and this boronic ester, widely used in medicinal chemistry.
• Pharmaceutical Intermediate Synthesis: Serves as a versatile precursor in the multi-step synthesis of novel drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Research & Development: Used in creating advanced herbicides, fungicides, and insecticides with specific activity profiles.
• Material Science: Employed in the synthesis of organic semiconductors, liquid crystals, and polymers with tailored electronic or optical properties.
• Chemical Biology & Probe Development: Useful for synthesizing molecular probes and bioconjugates for studying biological systems.
• Scale-up Process Chemistry: Suitable for process development and pilot-scale manufacturing due to its stability compared to free boronic acids.

Basic Information

Product Name	5-Fluoro-2-Isopropoxyphenylboronic Acid Pinacol Ester
CAS No.	1497435-85-4
Molecular Formula	C15H22BFO3
Molecular Weight	280.14 g/mol
Synonyms	5-Fluoro-2-isopropoxybenzeneboronic acid pinacol ester; 2-(5-Fluoro-2-isopropoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; (5-Fluoro-2-isopropoxyphenyl)boronic acid pinacol ester; Pinacol (5-fluoro-2-isopropoxyphenyl)boronate; Boronic acid, B-(5-fluoro-2-isopropoxyphenyl)-, 1,1,1,1-tetramethyl-2,2-diethyl ester; CAS 1497435-85-4
EINECS	Contact for details

Quality Control

Our 5-Fluoro-2-Isopropoxyphenylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and process chemistry. Certificates of Analysis (COA) with detailed chromatographic data (HPLC/GC) and spectroscopic confirmation (NMR) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.