Description

(S)-3,3'-Bis(3,5-Diphenyl)Phenyl-1,1'-Binaphthyl-2,2'-Diyl Hydrogen Phosphate is a sophisticated chiral phosphoric acid derivative, widely recognized as a highly effective organocatalyst and chiral resolving agent. Its value lies in its ability to induce exceptional enantioselectivity in a broad range of asymmetric synthetic transformations, enabling the production of high-purity chiral intermediates. This compound is essential for research and development laboratories and production facilities in the pharmaceutical, agrochemical, and fine chemical industries.

Application

• Asymmetric Organocatalysis: As a privileged Brønsted acid catalyst for enantioselective reactions including Friedel-Crafts alkylations, transfer hydrogenations, and Mannich reactions.
• Chiral Resolution: Employed as a chiral selector for the separation of enantiomers via diastereomeric salt formation or in chiral stationary phases for analytical chromatography.
• Pharmaceutical Intermediate Synthesis: Critical for the asymmetric synthesis of active pharmaceutical ingredients (APIs) and key chiral building blocks requiring high optical purity.
• Ligand Precursor: Serves as a precursor for the synthesis of chiral phosphoramidite and phosphite ligands used in transition metal catalysis.
• Material Science Research: Investigated for the development of chiral functional materials, such as circularly polarized luminescence (CPL) emitters and asymmetric sensors.
• Academic & Industrial R&D: A fundamental tool for methodology development in academic laboratories and process chemistry optimization in industrial settings.

Basic Information

Item	Detail
Product Name	(S)-3,3'-Bis(3,5-Diphenyl)Phenyl-1,1'-Binaphthyl-2,2'-Diyl Hydrogen Phosphate
CAS No.	1496637-05-8
Molecular Formula	C66H44O4P
Molecular Weight	941.01 g/mol
Synonyms	(S)-TRIP; (S)-3,3'-Bis(3,5-diphenylphenyl)-1,1'-binaphthyl-2,2'-diyl hydrogenphosphate; (S)-3,3'-Bis[3,5-bis(phenyl)phenyl]-1,1'-binaphthyl-2,2'-diyl hydrogen phosphate; (S)-Phosphoric acid di[1,1'-binaphthalene-2,2'-diyl] 3,3'-bis(3,5-diphenylphenyl) ester; Chiral phosphoric acid catalyst TRIP; (S)-TRIP PA; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Every batch of our (S)-3,3'-Bis(3,5-Diphenyl)Phenyl-1,1'-Binaphthyl-2,2'-Diyl Hydrogen Phosphate is produced and tested under strict quality management systems. We guarantee high chemical and optical purity to meet the rigorous demands of asymmetric synthesis. Comprehensive analytical testing, including HPLC for assay and enantiomeric excess (ee) determination, is performed. A Certificate of Analysis (COA) detailing purity, specific rotation, and identity is provided with each shipment to ensure full traceability and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light). For long-term storage, consider storing under an inert atmosphere to maintain optimal catalytic activity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (HPLC)	≥ 99.0% ee
Specific Rotation	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.