Description

2-(4,4-Difluorocyclohexyl)Ethan-1-Ol is a valuable fluorinated alcohol intermediate characterized by its cyclohexyl backbone and terminal hydroxyl group. This compound matters for its role in introducing both lipophilicity and specific steric properties into more complex molecules, which is critical for fine-tuning the activity and metabolic profile of target compounds. Pharmaceutical and agrochemical researchers need it primarily for use as a key building block in the synthesis of novel active ingredients, where its difluorocyclohexyl moiety can significantly influence bioavailability and binding affinity.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, metabolic diseases, and oncology.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the fluorinated cyclohexyl group can enhance compound stability, lipophilicity, and target interaction.
• Liquid Crystal & Advanced Material Synthesis: Serves as a precursor for fluorinated monomers and additives that impart specific dielectric and optical properties to advanced polymers and liquid crystal displays (LCDs).
• Organic Synthesis & Catalysis: Employed as a chiral auxiliary or a specialized reagent in asymmetric synthesis and transition-metal catalyzed reactions to construct complex molecular architectures.
• Flavor & Fragrance Industry: Potential use as an intermediate for synthesizing novel, stable fragrance molecules with unique olfactory characteristics.

Basic Information

Product Name	2-(4,4-Difluorocyclohexyl)Ethan-1-Ol
CAS No.	1494590-78-1
Molecular Formula	C8H14F2O
Molecular Weight	164.19 g/mol
Synonyms	2-(4,4-Difluorocyclohexyl)ethanol; 4,4-Difluorocyclohexaneethanol; 2-(4,4-Difluorocyclohexyl)ethyl alcohol; (4,4-Difluorocyclohexyl)ethanol; 1494590-78-1; 2-(4,4-Difluorocyclohexyl)ethan-1-ol; Ethanol, 2-(4,4-difluorocyclohexyl)-
EINECS	Contact for details

Quality Control

Our 2-(4,4-Difluorocyclohexyl)Ethan-1-Ol is produced under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent chemical identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply and traceability for your research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). For long-term storage, consider using desiccants or storing under an inert atmosphere (e.g., nitrogen or argon) to maintain product integrity and prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.