Description

4-[[2-[2-[(6-Chlorohexyl)Oxy]Ethoxy]Ethyl]Amino]-4-Oxobutanoic Acid is a specialized bifunctional organic compound featuring a reactive chloroalkyl terminus and a carboxylic acid group, linked via a flexible polyether-amide spacer. This unique structure makes it a valuable intermediate for the synthesis of targeted drug delivery systems, polymer conjugates, and advanced materials. It is primarily sought by research institutions and manufacturers in the pharmaceutical, bioconjugation, and specialty polymer industries for developing novel therapeutic agents and functionalized materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of antibody-drug conjugates (ADCs) and other targeted therapeutics.
• Bioconjugation Linker: Used to covalently attach drugs, probes, or polymers to biomolecules like proteins, peptides, or antibodies.
• Polymer Modification: Serves as a functional monomer or cross-linking agent for creating stimuli-responsive or biodegradable polymers.
• Prodrug Synthesis: Employed in designing prodrugs with tailored release profiles and improved bioavailability.
• Material Science: Used in surface functionalization and the creation of hydrogels or coatings with specific biological activities.
• Research & Development: A critical reagent in chemical biology and medicinal chemistry research for exploring new therapeutic modalities.

Basic Information

Item	Details
Product Name	4-[[2-[2-[(6-Chlorohexyl)Oxy]Ethoxy]Ethyl]Amino]-4-Oxobutanoic Acid
CAS No.	1488363-39-8
Molecular Formula	C14H26ClNO5
Molecular Weight	323.81 g/mol
Synonyms	4-({2-[2-(6-Chlorohexyloxy)ethoxy]ethyl}amino)-4-oxobutanoic acid; 6-Chlorohexyl-PEG2-acid; 6-Chlorohexyl-PEG2-C2-acid; 2-[2-(6-Chlorohexyloxy)ethoxy]-N-(2-carboxyethyl)acetamide; N-(2-Carboxyethyl)-2-[2-(6-chlorohexyloxy)ethoxy]acetamide; 4-Oxo-4-({2-[2-(6-chlorohexyloxy)ethoxy]ethyl}amino)butanoic acid; 6-Chloro-PEG2-C2-acid; Chlorohexyl-PEG2-C2-acid
EINECS	Contact for details

Quality Control

Our production of 4-[[2-[2-[(6-Chlorohexyl)Oxy]Ethoxy]Ethyl]Amino]-4-Oxobutanoic Acid adheres to stringent quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and structural integrity. Certificates of Analysis (COA) with detailed specifications are provided to support your R&D and cGMP manufacturing requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. Due to its hygroscopic nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.