Description

Ticagrelor Related Compound 90 Hcl is a high-purity chemical reference standard, specifically identified as a related substance of the antiplatelet drug Ticagrelor. This compound is critical for pharmaceutical research and development, serving as a key impurity marker to ensure drug safety, efficacy, and regulatory compliance. It is primarily required by analytical laboratories, quality control departments, and R&D teams in the pharmaceutical and fine chemical industries for method development, validation, and routine batch analysis.

Application

• Pharmaceutical Impurity Profiling: Used as a certified reference standard for the identification and quantification of specific impurities in Ticagrelor Active Pharmaceutical Ingredient (API) and finished drug products.
• Analytical Method Development & Validation: Essential for developing and validating stability-indicating HPLC/UPLC methods in compliance with ICH Q2(R1) and Q3B(R2) guidelines.
• Quality Control & Batch Release: Employed in routine QC testing to monitor impurity levels and ensure batch-to-batch consistency of Ticagrelor.
• Regulatory Submissions: Supports regulatory filings (e.g., for FDA, EMA) by providing necessary impurity characterization and control data.
• Stability Studies: Acts as a marker compound in forced degradation and long-term stability studies of Ticagrelor formulations.
• Research & Synthesis: Useful for synthetic chemists studying the degradation pathways or metabolism of Ticagrelor.

Basic Information

Product Name	Ticagrelor Related Compound 90 Hcl
CAS No.	1487958-68-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Ticagrelor Impurity 90 Hcl; Ticagrelor Related Substance 90 Hcl; Ticagrelor EP Impurity 90 Hcl; Ticagrelor USP Related Compound 90 Hcl; (1S,2S,3R,5S)-3-[7-{[(1R,2S)-2-(3,4-Difluorophenyl)cyclopropyl]amino}-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)cyclopentane-1,2-diol hydrochloride
EINECS	Contact for details

Quality Control

Our Ticagrelor Related Compound 90 Hcl is manufactured under strict quality systems and undergoes rigorous analytical testing to ensure it meets the high-purity standards required for pharmaceutical reference materials. Each batch is characterized and confirmed by advanced techniques including HPLC, MS, and NMR. A comprehensive Certificate of Analysis (COA) is provided, detailing purity, identity, and impurity profile, supporting compliance with pharmacopeial (USP/EP) and ICH guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Individual impurity: ≤ 1.0% Total impurities: ≤ 5.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.