Description

2-Ethoxy-1-Fluoro-4-Methylbenzene is a high-purity fluorinated aromatic ether building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where its unique substitution pattern enables precise molecular modifications. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce fluorine and alkoxy functionalities into complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where the fluorine atom enhances biological activity and environmental stability.
• Liquid Crystal Materials: Acts as a precursor in the manufacture of fluorinated components for liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs).
• Organic Electronic Materials: Employed in the development of novel semiconductors and charge-transport materials for electronic devices.
• Chemical Research & Development: A valuable reagent for method development and exploring new fluorination and etherification pathways in academic and industrial labs.
• Specialty Polymer Modifier: Can be incorporated as a monomer or additive to impart specific solubility, thermal, or optical properties to high-performance polymers.

Basic Information

Product Name	2-Ethoxy-1-Fluoro-4-Methylbenzene
CAS No.	1486959-73-2
Molecular Formula	C9H11FO
Molecular Weight	154.18 g/mol
Synonyms	1-Ethoxy-2-fluoro-4-methylbenzene; 2-Fluoro-4-methylanisole; 4-Methyl-2-fluoroanisole; 2-Fluoro-1-ethoxy-4-methylbenzene; 1-Fluoro-2-ethoxy-4-methylbenzene; 4-Methyl-2-fluoro-1-ethoxybenzene; 2-Fluoro-4-methylphenetole; FEMA 4606 (related compound identifier)
EINECS	Contact for details

Quality Control

Our 2-Ethoxy-1-Fluoro-4-Methylbenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, impurity profile, and physical properties are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible materials. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.485 - 1.495
Density (20°C)	1.05 - 1.15 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.