Description

3-(Trifluoromethoxy)Propanoic Acid is a specialized fluorinated organic acid building block. This compound is valued for its unique trifluoromethoxy group, which imparts enhanced metabolic stability, lipophilicity, and electronic properties to target molecules. It is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients. The compound serves as a critical intermediate for introducing the -OCF3 moiety into complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) with improved bioavailability and metabolic resistance.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the trifluoromethoxy group enhances biological activity.
• Material Science Research: Serves as a monomer or modifier in the creation of specialty polymers and coatings with unique surface properties.
• Ligand and Catalyst Development: Employed in the design of novel ligands and organocatalysts for asymmetric synthesis and other advanced chemical transformations.
• Fluorine Chemistry Research: A valuable reagent for academic and industrial research focused on incorporating fluorine and fluorinated alkoxy groups into organic molecules.

Basic Information

Product Name	3-(Trifluoromethoxy)Propanoic Acid
CAS No.	1483237-81-5
Molecular Formula	C4H5F3O3
Molecular Weight	158.08 g/mol
Synonyms	3-(Trifluoromethoxy)propionic Acid; Propanoic Acid, 3-(Trifluoromethoxy)-; 3-(Trifluoromethoxy)propanoic Acid; 2-(Trifluoromethoxy)ethanecarboxylic Acid; 3-(Trifluoromethoxy)propanoic Acid CAS 1483237-81-5; TFMPA; OCF3-CH2-CH2-COOH
EINECS	Contact for details

Quality Control

Our 3-(Trifluoromethoxy)Propanoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, impurity profile, and physical characteristics. Our quality commitment ensures the material meets the stringent requirements for research and process development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and oxidizing agents. Recommended storage temperature is 2-8°C for long-term stability. The container should be kept tightly sealed to minimize exposure to moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.