Description

(R)-2-((((9H-Fluoren-9-Yl)Methoxy)Carbonyl)Amino)-5-Methoxy-5-Oxopentanoic Acid is a high-purity, chiral Fmoc-protected amino acid derivative essential for advanced peptide synthesis. This compound serves as a critical building block for the controlled introduction of specific amino acid sequences, enabling the creation of complex peptides with defined stereochemistry. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic peptides, peptidomimetics, and biochemical probes.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the automated, stepwise construction of custom peptides, particularly where the (R)-configuration of the amino acid is required.
• Pharmaceutical Research & Development: Used in the discovery and synthesis of peptide-based drug candidates targeting various diseases, including metabolic disorders and cancers.
• Bioconjugation and Labeling: Facilitates the site-specific modification of peptides with reporter molecules, tags, or other functional groups for diagnostic and imaging applications.
• Combinatorial Chemistry Libraries: Serves as a valuable component in generating diverse libraries of peptide compounds for high-throughput screening against biological targets.
• Academic Research: Employed in biochemistry and molecular biology laboratories to study protein-protein interactions, enzyme mechanisms, and cellular signaling pathways using synthetic peptide tools.

Basic Information

Product Name	(R)-2-((((9H-Fluoren-9-Yl)Methoxy)Carbonyl)Amino)-5-Methoxy-5-Oxopentanoic Acid
CAS No.	1481642-14-1
Molecular Formula	C21H21NO6
Molecular Weight	383.40 g/mol
Synonyms	Fmoc-D-Glu(OMe)-OH; Fmoc-D-Glutamic Acid 5-Methyl Ester; (R)-Fmoc-Glu(OMe)-OH; (R)-2-(((9-Fluorenylmethoxy)carbonyl)amino)-5-methoxy-5-oxopentanoic acid; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-D-glutamic acid 5-methyl ester; D-Fmoc-Glu(OMe)-OH; Fmoc-D-Glu-OMe; Fmoc-D-Glutamic Acid γ-Methyl Ester
EINECS	Contact for details

Quality Control

Our (R)-2-((((9H-Fluoren-9-Yl)Methoxy)Carbonyl)Amino)-5-Methoxy-5-Oxopentanoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral analysis to confirm stereochemical integrity, ensuring compliance with research and pharmaceutical-grade standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.