Description

3-({[(9H-Fluoren-9-Yl)Methoxy]Carbonyl}Amino)-2,2,3-Trimethylbutanoic Acid is a specialized, high-purity building block designed for advanced organic synthesis. This compound is valued for its role as a protected amino acid derivative, offering precise control in complex molecular assembly. It is primarily utilized by research institutions and pharmaceutical development teams working on peptide-based therapeutics, novel drug candidates, and sophisticated fine chemical intermediates.

Application

• Solid-Phase Peptide Synthesis (SPPS): Serves as a key Fmoc-protected amino acid building block for the controlled assembly of peptide chains.
• Pharmaceutical Intermediate: Used in the research and development of novel active pharmaceutical ingredients (APIs), particularly those with complex, sterically hindered structures.
• Proteomics Research: Employed in the synthesis of custom peptides for biochemical assays, enzyme studies, and protein-protein interaction analysis.
• Combinatorial Chemistry: A valuable reagent for generating diverse chemical libraries in drug discovery platforms.
• Bioconjugation: Facilitates the site-specific modification of biomolecules for diagnostic or therapeutic applications.
• Academic & Industrial R&D: Essential for synthetic chemistry research focused on developing new methodologies and complex target molecules.

Basic Information

Product Name	3-({[(9H-Fluoren-9-Yl)Methoxy]Carbonyl}Amino)-2,2,3-Trimethylbutanoic Acid
CAS No.	1480824-29-0
Molecular Formula	C22H25NO4
Molecular Weight	367.44 g/mol
Synonyms	Fmoc-2,2,3-Trimethyl-β-alanine; Fmoc-Tma-OH; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-2,2,3-trimethyl-β-alanine; 3-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-2,2,3-trimethylbutanoic acid; Fmoc-3-amino-2,2,3-trimethylbutyric acid; N-Fmoc-2,2,3-trimethyl-β-alanine; (2,2,3-Trimethyl-3-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}butanoic acid)
EINECS	Contact for details

Quality Control

Our production of 3-({[(9H-Fluoren-9-Yl)Methoxy]Carbonyl}Amino)-2,2,3-Trimethylbutanoic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity suitable for sensitive research and development applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We commit to specifications that meet the exacting standards required for pharmaceutical intermediates and advanced synthetic chemistry.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); containers must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 98.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.