Description

tert-Butyl n-(3-Fluoro-4-Methoxyphenyl)Carbamate is a high-purity, advanced pharmaceutical intermediate characterized by its specific fluorine and methoxy substitution pattern. This compound is critical for medicinal chemistry research and development, serving as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce this unique aromatic moiety into target molecules.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of potential drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to explore new chemical entities.
• Process Chemistry Development: Serves as a starting material or intermediate in scaling up synthetic routes for Active Pharmaceutical Ingredients (APIs).
• Agrochemical Synthesis: Employed in the research and development of new herbicides or pesticides where the fluoro-methoxyphenyl group is a desired pharmacophore.
• Fine Chemical Production: Used in the custom synthesis of complex, high-value specialty chemicals for various industrial applications.
• Academic Research: A valuable reagent for universities and research institutes studying organic synthesis methodologies and heterocyclic chemistry.

Basic Information

Product Name	tert-Butyl n-(3-Fluoro-4-Methoxyphenyl)Carbamate
CAS No.	1480520-42-0
Molecular Formula	C12H16FNO3
Molecular Weight	241.26 g/mol
Synonyms	tert-Butyl (3-Fluoro-4-methoxyphenyl)carbamate; Carbamic acid, N-(3-fluoro-4-methoxyphenyl)-, 1,1-dimethylethyl ester; BOC-3-Fluoro-4-methoxy-aniline; N-Boc-3-Fluoro-4-methoxyaniline; 1,1-Dimethylethyl N-(3-fluoro-4-methoxyphenyl)carbamate; tert-Butyl N-(3-fluoro-4-methoxyphenyl)carbamate; 3-Fluoro-4-methoxy-phenyl-carbamic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl n-(3-Fluoro-4-Methoxyphenyl)Carbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and consistency for critical R&D and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.