Description

Hydroxy-(3-Trifluoromethoxy-Phenyl)-Acetic Acid Methyl Ester is a high-value fluorinated aromatic ester building block. This compound is significant for its trifluoromethoxy (-OCF₃) and hydroxyphenylacetic acid ester functionalities, which are key motifs in modern pharmaceutical and agrochemical design. It is primarily needed by R&D chemists and process development scientists in the life sciences sector for synthesizing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in CNS, anti-inflammatory, and antiviral research.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the trifluoromethoxy group enhances bioactivity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials and organic light-emitting diodes.
• Advanced Polymer Chemistry: Incorporated as a monomer or modifier to create specialty polymers with unique thermal and chemical resistance properties.
• Chemical Research & Development: Employed as a versatile building block in medicinal chemistry and material science for structure-activity relationship (SAR) studies.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the scale-up and production of client-specific target molecules.

Basic Information

Product Name	Hydroxy-(3-Trifluoromethoxy-Phenyl)-Acetic Acid Methyl Ester
CAS No.	1480321-04-7
Molecular Formula	C₁₀H₉F₃O₄
Molecular Weight	250.17 g/mol
Synonyms	Methyl 2-Hydroxy-2-(3-(trifluoromethoxy)phenyl)acetate; 2-Hydroxy-2-[3-(trifluoromethoxy)phenyl]acetic Acid Methyl Ester; (3-Trifluoromethoxyphenyl)(hydroxy)acetic Acid Methyl Ester; Methyl (3-Trifluoromethoxyphenyl)(hydroxy)acetate; α-Hydroxy-3-(trifluoromethoxy)benzeneacetic Acid Methyl Ester; Methyl α-Hydroxy-α-(3-trifluoromethoxyphenyl)acetate; Hydroxy(3-trifluoromethoxyphenyl)acetate Methyl Ester
EINECS	Contact for details

Quality Control

Our Hydroxy-(3-Trifluoromethoxy-Phenyl)-Acetic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage, consider inert atmosphere conditions to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Assay	≥ 96.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.