Description

(1R,2R)-2-[(4S,11Br)-3,5-Dihydro-4H-Dinaphtho[2,1-C:1',2'-E]Phosphepin-4-Yl]-1,2-Diphenylethanamine, Min. 97% is a high-purity, chiral phosphine-amine hybrid ligand, a sophisticated organocatalyst crucial for inducing stereoselectivity in complex synthetic transformations. Its value lies in its ability to provide exceptional enantiomeric control in asymmetric synthesis, a critical requirement for developing active pharmaceutical ingredients (APIs) and advanced materials. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-quality chiral auxiliaries to streamline their R&D and scale-up processes.

Application

• Asymmetric Catalysis: As a privileged chiral ligand for transition metal-catalyzed reactions, including hydrogenation, cross-coupling, and hydroformylation.
• Pharmaceutical Intermediate Synthesis: Enabling the stereoselective construction of complex molecular architectures for novel drug candidates and APIs.
• Agrochemical Research: Facilitating the development of enantiomerically pure pesticides and herbicides with improved efficacy and environmental profiles.
• Methodology Development: Serving as a key reagent in academic and industrial labs for discovering new asymmetric synthetic protocols.
• Fine Chemical Production: Used in the manufacture of specialty chemicals, flavors, and fragrances where chiral purity is paramount.
• Material Science: Potential application in the synthesis of chiral polymers or frameworks with unique optical or electronic properties.

Basic Information

Product Name	(1R,2R)-2-[(4S,11Br)-3,5-Dihydro-4H-Dinaphtho[2,1-C:1',2'-E]Phosphepin-4-Yl]-1,2-Diphenylethanamine, Min. 97%
CAS No.	1469882-57-2
Molecular Formula	C38H29BrNP
Molecular Weight	610.52 g/mol
Synonyms	(1R,2R)-2-[(4S,11Br)-3,5-Dihydro-4H-dinaphtho[2,1-c:1',2'-e]phosphepin-4-yl]-1,2-diphenylethanamine; (R,R)-2-[(S,Br)-DINAP-P-NH2]; Chiral Br-DINAP amine ligand; (1R,2R)-2-[(4S,11-bromo)-3,5-dihydro-4H-dinaphtho[2,1-c:1′,2′-e]phosphepin-4-yl]-1,2-diphenylethanamine; Bromo-DINAP-based amine ligand; Asymmetric phosphine-amine bidentate ligand.
EINECS	Contact for details

Quality Control

Every batch of our (1R,2R)-2-[(4S,11Br)-3,5-Dihydro-4H-Dinaphtho[2,1-C:1',2'-E]Phosphepin-4-Yl]-1,2-Diphenylethanamine undergoes rigorous analytical testing to ensure it meets the stringent purity and chiral integrity standards required for advanced synthetic applications. Our quality protocols are designed to support cGMP and ISO-guided manufacturing principles. A comprehensive Certificate of Analysis (COA) detailing purity (HPLC), chiral purity, and identity is provided with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry place. This compound is easily oxidized and light-sensitive; prolonged exposure to air or light may compromise purity and catalytic activity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	Min. 97.0%
Chiral Purity (HPLC)	Min. 99.0% ee
Water Content (KF)	Max. 0.5%
Residue on Ignition	Max. 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.