Description

2-((1S,4S)-4-Aminocyclohexyl)Acetonitrile is a high-purity chiral building block of significant importance in modern synthetic chemistry. Its value lies in its stereochemically defined cyclohexylamine backbone, which is crucial for constructing complex molecules with specific three-dimensional architectures. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, particularly where stereochemistry is a critical factor for biological activity.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), especially in central nervous system (CNS) and antiviral drug candidates.
• Agrochemical Synthesis: Used in the creation of advanced, stereoselective herbicides, fungicides, and insecticides where the specific spatial orientation of the molecule enhances efficacy.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis to induce high enantioselectivity in reactions.
• Peptidomimetics Research: Employed in the design and synthesis of peptide analogs and conformationally restricted scaffolds for drug discovery programs.
• Chemical Biology Probes: Utilized as a building block for creating molecular probes to study enzyme function and biological pathways.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis houses serving the fine chemical and life science industries.

Basic Information

Product Name	2-((1S,4S)-4-Aminocyclohexyl)Acetonitrile
CAS No.	1461869-58-8
Molecular Formula	C8H14N2
Molecular Weight	138.21 g/mol
Synonyms	(1S,4S)-4-(Cyanomethyl)cyclohexanamine; (1S,4S)-4-(2-Cyanoethyl)cyclohexanamine; (1S,4S)-4-Aminocyclohexaneacetonitrile; trans-4-Aminocyclohexylacetonitrile; 2-[(1S,4S)-4-Aminocyclohexyl]ethanenitrile; 4-Aminocyclohexylacetonitrile (trans-); (1S,4S)-4-(Cyanomethyl)cyclohexylamine
EINECS	Contact for details

Quality Control

Our 2-((1S,4S)-4-Aminocyhexyl)Acetonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC to ensure enantiomeric purity and identity confirmation. Certificates of Analysis (COA) detailing purity, chiral excess, and impurity profiles are provided with every shipment to guarantee consistent quality and traceability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.