Description

Acetylene-Peg4-Biotin Conjugate is a high-purity, specialized biochemical reagent designed for advanced bioconjugation and labeling applications. This compound is critical for researchers and developers requiring precise, stable linkages between biomolecules and detection systems or solid supports. It is primarily utilized in the pharmaceutical, diagnostic, and life science research sectors for applications such as targeted drug delivery, assay development, and proteomics. The product offers a reliable solution for creating biotinylated probes with controlled linker length and enhanced solubility.

Application

• Bioconjugation Reagent: For the site-specific labeling of proteins, antibodies, and other biomolecules with biotin.
• Drug Delivery System Development: As a key component in the synthesis of antibody-drug conjugates (ADCs) and targeted therapeutics.
• Diagnostic Assay Fabrication: Used in ELISA, lateral flow assays, and other immunoassays to create detection probes.
• Pull-down and Capture Experiments: Essential for affinity purification, mass spectrometry (MS) sample preparation, and protein interaction studies using streptavidin/avidin matrices.
• Cell Surface Labeling: For fluorescence-activated cell sorting (FACS) and imaging studies via biotin-streptavidin amplification.
• Material Science & Nanotechnology: Functionalization of nanoparticles, surfaces, and polymers for biosensor development.

Basic Information

Product Name	Acetylene-Peg4-Biotin Conjugate
CAS No.	1458576-00-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Biotin-PEG4-Alkyne; Alkyne-PEG4-Biotin; PEG4-Biotin Alkyne; N-(Biotinoyl)-N'-(propargyl-PEG4)-1,3-diaminopropane; Biotin-PEG4-Propargyl; Propargyl-PEG4-Biotin; 5-((3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-N-(prop-2-yn-1-yl)pentanamide-PEG4 conjugate
EINECS	Contact for details

Quality Control

Every batch of Acetylene-Peg4-Biotin Conjugate is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We ensure compliance with high-purity standards suitable for research and development use. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity (typically >95% by HPLC), and other critical specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This product is hygroscopic (moisture-sensitive) and should be allowed to equilibrate to room temperature in a dry environment before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMSO, DMF; Slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.