Description

4-Bromo-1,3-Dimethyl-1H-Pyrazole-5-Carbonitrile is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. Its core value lies in its versatile reactivity, serving as a key precursor for constructing complex molecular architectures in pharmaceutical and agrochemical research. This compound is primarily needed by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and crop protection industries for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and anti-inflammatory drug discovery programs.
• Agrochemical Synthesis: Used as a building block for creating new herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized pyrazole-based ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers or photoactive components, due to its electron-withdrawing nitrile and bromo substituents.
• Chemical Biology Probes: Utilized to create tagged or functionalized molecules for studying biological pathways and protein interactions.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects requiring this precise bromo-nitrile pyrazole scaffold.

Basic Information

Product Name	4-Bromo-1,3-Dimethyl-1H-Pyrazole-5-Carbonitrile
CAS No.	1454852-95-9
Molecular Formula	C6H6BrN3
Molecular Weight	200.04 g/mol
Synonyms	4-Bromo-1,3-dimethyl-5-cyanopyrazole; 4-Bromo-1,3-dimethylpyrazole-5-carbonitrile; 1,3-Dimethyl-4-bromo-1H-pyrazole-5-carbonitrile; 5-Cyano-4-bromo-1,3-dimethylpyrazole; 1H-Pyrazole-5-carbonitrile, 4-bromo-1,3-dimethyl-; 4-Bromo-1,3-dimethyl-1H-pyrazole-5-carbonitrile; 1454852-95-9
EINECS	Contact for details

Quality Control

Our 4-Bromo-1,3-Dimethyl-1H-Pyrazole-5-Carbonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container tightly sealed to prevent moisture absorption and contamination. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.