Description

(S)-[2’-Benzyl-[1,1’-Binaphthalen]-2-Yl]Diphenylphosphine is a high-value, chiral monophosphine ligand essential for asymmetric catalysis. Its unique steric and electronic properties enable the precise control of stereochemistry in critical bond-forming reactions. This compound is primarily required by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of enantiomerically pure intermediates and active ingredients.

Application

• Asymmetric Hydrogenation: A key ligand for the enantioselective reduction of prochiral olefins, enamines, and ketones in pharmaceutical API synthesis.
• Asymmetric Cross-Coupling Reactions: Employed in Buchwald-Hartwig amination and Suzuki-Miyaura coupling to create chiral biaryl and amine structures.
• Asymmetric Allylic Substitution: Facilitates the construction of chiral carbon centers with high enantiomeric excess.
• Pharmaceutical Intermediate Synthesis: Critical for producing enantiopure building blocks for drug candidates targeting CNS disorders, oncology, and infectious diseases.
• Agrochemical Product Development: Used in the synthesis of chiral herbicides, fungicides, and plant growth regulators.
• Academic & Industrial Research: A valuable tool for methodology development in academic labs and for scaling novel catalytic processes in industry.

Basic Information

Product Name	(S)-[2’-Benzyl-[1,1’-Binaphthalen]-2-Yl]Diphenylphosphine
CAS No.	1454319-47-1
Molecular Formula	C45H33P
Molecular Weight	604.72 g/mol
Synonyms	(S)-2'-Benzyl-2-(diphenylphosphino)-1,1'-binaphthyl; (S)-Benzyl-PHANEPHOS; (S)-2-(Diphenylphosphino)-2'-(phenylmethyl)-1,1'-binaphthalene; (S)-2'-(Benzyl)-2-(diphenylphosphino)-1,1'-binaphthyl; (S)-Benzyl-PHANEPHOS Ligand; (S)-Bz-PHANEPHOS; (S)-[2'-(Phenylmethyl)-[1,1'-binaphthalen]-2-yl]diphenylphosphine
EINECS	Contact for details

Quality Control

Every batch of our (S)-[2’-Benzyl-[1,1’-Binaphthalen]-2-Yl]Diphenylphosphine is manufactured and tested under strict quality management systems. We guarantee high chemical and chiral purity to meet the demanding requirements of catalytic applications. Comprehensive Certificates of Analysis (COA) are provided, detailing results for assay, enantiomeric excess, and key impurities.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C to prevent oxidation and degradation. Allow the container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.