Description

(R)-1-[Bis[3,5-Bis(1,1-Dimethylethyl)-4-Methoxyphenyl] Phosphino]-2-[(1R)-1-(Dicyclohexylphosphino)Ethyl]Ferrocene is a highly specialized, chiral ferrocenyl phosphine ligand designed for asymmetric catalysis. Its value lies in its ability to induce high enantioselectivity and catalytic activity in transition metal-catalyzed reactions, which is critical for producing single-enantiomer compounds. This ligand is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries who require precise stereochemical control in synthetic processes such as hydrogenation, cross-coupling, and hydroformylation.

Application

• As a chiral ligand for asymmetric hydrogenation of olefins, ketones, and imines in pharmaceutical intermediate synthesis.
• Enabling enantioselective cross-coupling reactions (e.g., Suzuki-Miyaura, Buchwald-Hartwig) for constructing chiral biaryl and C-N bonds.
• Catalyst component for asymmetric hydroformylation to produce chiral aldehydes.
• Use in academic and industrial R&D for developing novel catalytic methodologies.
• Potential application in the synthesis of agrochemicals requiring chiral active ingredients.
• Production of flavors, fragrances, and advanced materials where optical purity is paramount.

Basic Information

Item	Details
Product Name	(R)-1-[Bis[3,5-Bis(1,1-Dimethylethyl)-4-Methoxyphenyl] Phosphino]-2-[(1R)-1-(Dicyclohexylphosphino)Ethyl]Ferrocene
CAS No.	1453803-83-2
Molecular Formula	C55H78FeO2P2
Molecular Weight	873.00 g/mol (Contact for details)
Synonyms	(R)-Bis(3,5-di-tert-butyl-4-methoxyphenyl)((R)-1-(dicyclohexylphosphino)ethyl)ferrocenylphosphine; Josiphos SL-J009-1 type ligand; (R)-1-[(R)-1-[Bis(3,5-di-tert-butyl-4-methoxyphenyl)phosphino]ethyl]-2-(dicyclohexylphosphino)ferrocene; (R,R)-Bis(3,5-di-tert-butyl-4-methoxyphenyl)((R)-1-(dicyclohexylphosphino)ethyl)ferrocenylphosphine; Chiral Josiphos derivative; Asymmetric ferrocenyl diphosphine ligand
EINECS	Contact for details

Quality Control

Every batch of our chiral ligand undergoes rigorous analytical testing to ensure identity, purity, and enantiomeric excess meet the stringent requirements for catalytic applications. Standard quality protocols include HPLC, NMR (¹H, ³¹P), and chiral analysis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. Our quality management system supports compliance with cGMP standards for advanced synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Due to its sensitivity to oxidation, this material should be stored under an inert atmosphere (argon or nitrogen) in a cool, dry place. Recommended long-term storage temperature is 2-8°C. Allow the sealed container to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	Orange to red-brown solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Solubility	Soluble in common organic solvents (Toluene, DCM, THF)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.