Description

(1,1,1-Trifluoropropan-2-Yl)Hydrazine Hydrochloride is a high-purity fluorinated hydrazine derivative, a key building block in advanced organic synthesis. Its value lies in providing a trifluoromethyl-substituted hydrazine moiety, which is crucial for modulating the physicochemical and metabolic properties of target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, oncology, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for specialized ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Fluorinated Material Science: Employed in the synthesis of specialty polymers, liquid crystals, and electronic materials requiring fluorinated building blocks.
• Chemical Biology Probes: Utilized to create tagged molecules and activity-based probes for studying enzyme mechanisms and biological pathways.

Basic Information

Product Name	(1,1,1-Trifluoropropan-2-Yl)Hydrazine Hydrochloride
CAS No.	1453472-98-4
Molecular Formula	C3H7ClF3N2
Molecular Weight	172.55 g/mol
Synonyms	1,1,1-Trifluoro-2-hydrazinylpropane Hydrochloride; 2-Hydrazinyl-1,1,1-trifluoropropane Hydrochloride; (1,1,1-Trifluoro-2-propanyl)hydrazine Hydrochloride; 1,1,1-Trifluoropropan-2-ylhydrazine HCl; 2-Hydrazino-1,1,1-trifluoropropane Hydrochloride; 1,1,1-Trifluoro-2-hydrazinopropane Hydrochloride; TFPH-HCl
EINECS	Contact for details

Quality Control

Our (1,1,1-Trifluoropropan-2-Yl)Hydrazine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced research and GMP-grade production. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.