Description

Enoxacine-D8 Hydrate is a deuterium-labeled analog of the fluoroquinolone antibiotic enoxacin, specifically designed for use as an internal standard in quantitative analytical methods. This high-purity stable isotope-labeled compound is essential for ensuring accuracy and reliability in mass spectrometry-based analyses, where it corrects for variations in sample preparation and instrument response. It is a critical tool for researchers and quality control laboratories in the pharmaceutical, contract research organization (CRO), and academic sectors who require definitive data for drug metabolism, pharmacokinetic studies, and regulatory bioanalytical method development.

Application

• Internal Standard for LC-MS/MS: Primary application as a quantitative internal standard in Liquid Chromatography-Tandem Mass Spectrometry for the analysis of enoxacin and its metabolites.
• Pharmacokinetic & Metabolism Studies: Enables precise tracking and quantification of the parent drug in biological matrices (plasma, serum, urine, tissue) during ADME (Absorption, Distribution, Metabolism, and Excretion) research.
• Bioanalytical Method Development & Validation: Used to develop and validate robust, GLP/GCP-compliant analytical methods for clinical and non-clinical studies.
• Drug Impurity Profiling & Reference Standard: Serves as a certified reference material for identifying and quantifying process-related impurities or degradation products in pharmaceutical formulations.
• Environmental & Food Safety Testing: Applicable in residue analysis methods for monitoring fluoroquinolone antibiotics in environmental water samples or food products.

Basic Information

Product Name	Enoxacine-D8 Hydrate
CAS No.	1453100-62-3
Molecular Formula	C15H9D8FN4O3 • xH2O
Molecular Weight	Contact for details
Synonyms	1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-1,8-naphthyridine-3-carboxylic Acid-d8; Enoxacin-d8; Enoxacin Deuterated; Enoxacin (ethyl-d5, piperazine-2,2,5,5,6,6-d6); AT-2266-d8; CI-919-d8; PD-107779-d8; Flumark-d8
EINECS	Contact for details

Quality Control

Every batch of Enoxacine-D8 Hydrate is manufactured and analyzed under strict quality systems. We provide comprehensive analytical data to support its use in regulated environments. Certificates of Analysis (COA) are supplied with each shipment, detailing critical parameters such as isotopic purity, chemical purity, and residual solvent content. Our quality commitment ensures consistency and reliability for your most demanding analytical applications.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥98.0% (chemical purity)
Isotopic Purity	≥98.0 atom % D
Water Content (KF)	≤5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.