Description

2-Bromo-3-Chloro-6-Methoxyphenylboronic Acid is a highly functionalized arylboronic acid derivative, a crucial building block in modern synthetic organic chemistry. Its value lies in its ability to participate in key cross-coupling reactions, enabling the efficient construction of complex molecular architectures. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for the synthesis of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used to create complex, halogenated aromatic structures found in advanced herbicides, fungicides, and insecticides.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and semiconductors, where precise molecular structure is critical.
• Chemical Biology Probes: Useful for creating tagged molecules and bioconjugates for studying biological pathways and protein interactions.
• Custom Synthesis and Contract Manufacturing: A vital raw material for CROs and CDMOs offering bespoke chemical synthesis services to global clients.

Basic Information

Product Name	2-Bromo-3-Chloro-6-Methoxyphenylboronic Acid
CAS No.	1452575-89-1
Molecular Formula	C7H7BBrClO3
Molecular Weight	264.30 g/mol
Synonyms	(2-Bromo-3-chloro-6-methoxyphenyl)boronic acid; 2-Bromo-3-chloro-6-methoxybenzeneboronic acid; B-(2-Bromo-3-chloro-6-methoxyphenyl)boronic acid; 2-Bromo-3-chloro-6-methoxy-phenylboronic acid; Boronic acid, B-(2-bromo-3-chloro-6-methoxyphenyl)-; 1452575-89-1
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-3-Chloro-6-Methoxyphenylboronic Acid is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive cross-coupling applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles by HPLC, NMR, and other relevant techniques is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.