Description

2,5-Difluoro-4-Ethoxyphenylboronic Acid is a high-purity, multi-functional boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the precise construction of complex molecular architectures. It is primarily required by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used to construct complex, fluorinated active ingredients for next-generation herbicides, fungicides, and pesticides with enhanced efficacy.
• Liquid Crystal & OLED Materials: Serves as a building block for creating advanced fluorinated organic electronic materials used in displays and lighting.
• Polymer Chemistry: Employed in the synthesis of specialty polymers and functionalized materials with tailored properties.
• Chemical Biology & Proteomics: Utilized in the development of molecular probes and sensors due to its specific binding affinity.
• Academic & Contract Research: A valuable reagent for methodological development and discovery chemistry in research laboratories worldwide.

Basic Information

Product Name	2,5-Difluoro-4-Ethoxyphenylboronic Acid
CAS No.	1452575-83-5
Molecular Formula	C8H9BF2O3
Molecular Weight	201.97 g/mol
Synonyms	(2,5-Difluoro-4-ethoxyphenyl)boronic Acid; 4-Ethoxy-2,5-difluorophenylboronic Acid; B-(2,5-Difluoro-4-ethoxyphenyl)boronic Acid; 2,5-Difluoro-4-ethoxybenzeneboronic Acid; 1452575-83-5; Boronic acid, B-(2,5-difluoro-4-ethoxyphenyl)-; AKOS040759054
EINECS	Contact for details

Quality Control

Our 2,5-Difluoro-4-Ethoxyphenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and identity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee batch-to-batch consistency and support your regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.