Description

Fmoc-Dl-Thyronine CAS NO 1452575-06-2 is a protected, non-natural amino acid derivative specifically engineered for advanced peptide synthesis and pharmaceutical research. This compound is a critical building block for the solid-phase synthesis of complex peptides and peptidomimetics, offering precise control over molecular architecture. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers developing novel therapeutic agents, diagnostic tools, and biochemical probes.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the controlled, sequential assembly of peptides using Fmoc-chemistry protocols.
• Pharmaceutical Research & Development: Used in the discovery and development of peptide-based drugs, hormone analogs, and targeted therapeutics.
• Bioconjugation: Serves as a linker or modified amino acid for attaching peptides to other molecules, surfaces, or carriers in drug delivery systems.
• Chemical Biology & Proteomics: Employed to synthesize custom peptides for studying protein-protein interactions, enzyme activity, and cellular signaling pathways.
• Reference Standard Production: Acts as a high-purity standard for analytical method development and quality control in peptide manufacturing.

Basic Information

Product Name	Fmoc-Dl-Thyronine
CAS No.	1452575-06-2
Molecular Formula	C24H21NO6
Molecular Weight	419.43 g/mol
Synonyms	Fmoc-DL-Thyronine; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-DL-thyronine; DL-Thyronine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-; Fmoc-Thyronine; N-Fmoc-DL-thyronine; (RS)-2-[[4-(4-Hydroxyphenoxy)-3,5-diiodophenyl]methylamino]-3-[9H-fluoren-9-ylmethoxycarbonylamino]propanoic Acid
EINECS	Contact for details

Quality Control

Our Fmoc-Dl-Thyronine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and chiral analysis to verify the DL-mixture. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with research and cGMP-grade material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as specified on the label. This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.