Description

n-(1H-Indol-2-Ylcarbonyl)Norleucine is a specialized, high-purity synthetic amino acid derivative designed for advanced research and development. This compound matters as a crucial building block in the synthesis of novel peptides and peptidomimetics, offering researchers precise control over molecular structure. It is primarily needed by pharmaceutical R&D teams, biotechnology companies, and academic institutions focused on drug discovery, particularly in developing targeted therapies and enzyme inhibitors.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel therapeutic peptides and peptidomimetic drug candidates.
• Biochemical Research: Used as a specialized substrate or inhibitor in enzymatic studies and proteomics research.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to optimize the potency and selectivity of lead compounds.
• Peptide Synthesis: Acts as a modified amino acid residue for the solid-phase or solution-phase construction of custom peptides with enhanced properties.
• Chemical Biology Probes: Incorporated into molecular probes for studying protein-protein interactions and cellular signaling pathways.
• Academic & Institutional R&D: Utilized in university and government laboratories for fundamental research in organic chemistry and bioorganic chemistry.

Basic Information

Product Name	n-(1H-Indol-2-Ylcarbonyl)Norleucine
CAS No.	1452575-02-8
Molecular Formula	C16H19N3O3
Molecular Weight	301.34 g/mol
Synonyms	Norleucine, N-[(1H-indol-2-yl)carbonyl]-; N-(1H-Indole-2-carbonyl)-L-norleucine; 2-[(1H-Indol-2-ylcarbonyl)amino]hexanoic acid; (S)-2-((1H-Indole-2-carboxamido)hexanoic acid; L-Norleucine, N-(1H-indol-2-ylcarbonyl)-; Nα-(1H-Indole-2-carbonyl)-L-norleucine; Nα-Indole-2-carbonyl-L-norleucine; N-Indole-2-carbonylnorleucine
EINECS	Contact for details

Quality Control

Our n-(1H-Indol-2-Ylcarbonyl)Norleucine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.