Description

Potassium 2-{4-(n-Boc)-Piperazin-1-Yl}Ethoxymethyltrifluoroborate is a high-value organotrifluoroborate salt, a crucial building block in modern synthetic chemistry. Its primary value lies in its stability and utility as a coupling partner in transition metal-catalyzed cross-coupling reactions, such as the Suzuki-Miyaura reaction, enabling the efficient construction of complex molecules. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-purity intermediates for drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing piperazine and protected amine motifs.
• Suzuki-Miyaura Cross-Coupling: A stable and effective organoboron reagent for palladium-catalyzed carbon-carbon bond formation, critical for creating biaryl and heterobiaryl structures.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides requiring specific, complex molecular architectures.
• Chemical Biology & Probe Development: Serves as a versatile handle for the synthesis of molecular probes and tools used in biochemical and cellular studies.
• Material Science Research: Potential precursor for creating functional organic materials and ligands for catalysis.
• Process Chemistry & Scale-up: Suitable for optimization and scaling in pilot plants and commercial manufacturing of fine chemicals.

Basic Information

Item	Details
Product Name	Potassium 2-{4-(n-Boc)-Piperazin-1-Yl}Ethoxymethyltrifluoroborate
CAS No.	1452383-14-0
Molecular Formula	C12H22BF3KN2O3
Molecular Weight	334.13 g/mol
Synonyms	Potassium (2-((4-(tert-Butoxycarbonyl)piperazin-1-yl)ethoxy)methyl)trifluoroborate; Potassium Trifluoro((2-(4-(tert-butoxycarbonyl)piperazin-1-yl)ethoxy)methyl)borate; N-Boc-4-(2-(Trifluoroborato)ethoxymethyl)piperazine; Potassium (2-(4-Boc-piperazin-1-yl)ethoxymethyl)trifluoroborate; 1-Boc-4-(2-(Trifluoroboratomethoxy)ethyl)piperazine Potassium Salt; (2-(4-(tert-Butoxycarbonyl)piperazin-1-yl)ethoxymethyl)trifluoroborate Potassium Salt
EINECS	Contact for details

Quality Control

Our Potassium 2-{4-(n-Boc)-Piperazin-1-Yl}Ethoxymethyltrifluoroborate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR (1H, 13C, 19F, 11B) and HPLC analysis, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and purity. Allow the sealed container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥95%
19F NMR Purity	≥95%
11B NMR Purity	≥95%
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.