Description

(2-Fluoro-4-(Morpholinomethyl)Phenyl)Boronic Acid is a sophisticated boronic acid derivative featuring a fluorinated aromatic core and a morpholine moiety, making it a valuable building block in modern synthetic chemistry. This compound is essential for facilitating Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex biaryl structures. It is primarily utilized by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used to create novel herbicides, fungicides, and insecticides by constructing complex aromatic scaffolds.
• Material Science: Serves as a monomer or cross-linker in the development of advanced polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Proteomics: Employed in the design and synthesis of molecular probes, inhibitors, and activity-based probes for studying enzyme function.
• Catalyst & Ligand Development: Utilized to synthesize novel ligands for transition metal catalysts used in asymmetric synthesis.
• Library Synthesis for Drug Discovery: A crucial building block in parallel and combinatorial chemistry for generating diverse compound libraries for high-throughput screening.

Basic Information

Product Name	(2-Fluoro-4-(Morpholinomethyl)Phenyl)Boronic Acid
CAS No.	1451393-46-6
Molecular Formula	C11H15BFNO3
Molecular Weight	239.06 g/mol
Synonyms	[2-Fluoro-4-(morpholin-4-ylmethyl)phenyl]boronic acid; 2-Fluoro-4-(morpholinomethyl)benzeneboronic acid; 4-(2-Fluoro-4-boronobenzyl)morpholine; B-[2-Fluoro-4-(morpholinomethyl)phenyl]boronic acid; (2-Fluoro-4-morpholinomethylphenyl)boronic acid; 1451393-46-6; Boronic acid, B-[2-fluoro-4-(4-morpholinylmethyl)phenyl]-; AKOS025310647
EINECS	Contact for details

Quality Control

Our (2-Fluoro-4-(Morpholinomethyl)Phenyl)Boronic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and scale-up applications. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting key parameters such as assay purity and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.