Description

3-(Benzyloxy)-5-(Trifluoromethyl)Phenylboronic Acid is a specialized organoboron compound serving as a key synthetic intermediate in advanced organic chemistry. Its value lies in the unique reactivity of the boronic acid group, enabling efficient cross-coupling reactions to construct complex molecular architectures. This high-purity building block is essential for researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries, facilitating the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial building block in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly those containing the trifluoromethyl group for enhanced metabolic stability and lipophilicity.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where the introduction of specific aromatic systems can modulate biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands or metal-organic frameworks (MOFs) used in catalysis and material science.
• Organic Electronic Materials: Employed in the synthesis of conjugated polymers and small molecules for applications in OLEDs, OFETs, and other electronic devices.
• Chemical Biology Probes: Useful for synthesizing tagged molecules or inhibitors used to study biological pathways and protein functions.
• Custom Synthesis and R&D: A valuable reagent for contract research organizations (CROs) and academic laboratories engaged in exploratory chemistry and method development.

Basic Information

Product Name	3-(Benzyloxy)-5-(Trifluoromethyl)Phenylboronic Acid
CAS No.	1451393-42-2
Molecular Formula	C14H12BF3O3
Molecular Weight	296.05 g/mol
Synonyms	[3-(Benzyloxy)-5-(trifluoromethyl)phenyl]boronic acid; 3-Benzyloxy-5-(trifluoromethyl)benzeneboronic acid; 5-(Benzyloxy)-3-(trifluoromethyl)phenylboronic Acid; (3-(Benzyloxy)-5-(trifluoromethyl)phenyl)boronic acid; Boronic acid, B-[3-(phenylmethoxy)-5-(trifluoromethyl)phenyl]-; 1451393-42-2
EINECS	Contact for details

Quality Control

Every batch of 3-(Benzyloxy)-5-(Trifluoromethyl)Phenylboronic Acid is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality assurance protocols are designed to meet the stringent requirements of research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity (typically ≥95% by HPLC), assay, and impurity profiles is provided with each shipment to support your quality management system.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is easily oxidized; for long-term storage, consider keeping under an inert atmosphere such as nitrogen or argon to maintain optimal purity and shelf life. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Assay	≥ 95%
Water Content (KF)	≤ 1.0%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.