Description

(2-Chloro-3,5-Difluorophenyl)Boronic Acid is a high-purity, multi-functional boronic acid derivative essential for modern synthetic chemistry. Its core value lies in enabling precise carbon-carbon bond formation via the Suzuki-Miyaura cross-coupling reaction, a cornerstone for constructing complex molecular architectures. This compound is critically needed by R&D and production teams in the pharmaceutical, agrochemical, and advanced materials sectors for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel active pharmaceutical ingredients (APIs), especially in drug discovery programs targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Material Science: Serves as a monomer or cross-linking agent in the development of organic electronic materials, such as polymers for OLEDs and sensors.
• Chemical Research: A versatile reagent in academic and industrial laboratories for methodology development and the synthesis of complex, fluorinated aromatic compounds.
• Ligand & Catalyst Development: Utilized to create novel boron-containing ligands for asymmetric catalysis and transition metal complexes.

Basic Information

Product Name	(2-Chloro-3,5-Difluorophenyl)Boronic Acid
CAS No.	1451393-37-5
Molecular Formula	C6H4BClF2O2
Molecular Weight	191.36 g/mol
Synonyms	2-Chloro-3,5-difluorophenylboronic Acid; (2-Chloro-3,5-difluorophenyl)boronic acid; B-(2-Chloro-3,5-difluorophenyl)boronic Acid; 2-Chloro-3,5-difluorobenzeneboronic Acid; 1451393-37-5; Boronic acid, B-(2-chloro-3,5-difluorophenyl)-; AKOS026712194
EINECS	Contact for details

Quality Control

Every batch of (2-Chloro-3,5-Difluorophenyl)Boronic Acid is manufactured and tested under strict quality management systems. We ensure compliance with rigorous internal specifications, which are designed to meet the demanding requirements of advanced synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.