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4-Fluoro-3-(2-Chloro-Phenylcarbamoyl)Phenylboronic Acid CAS NO 1451393-31-9


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CAS No.:1451393-31-9

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

4-Fluoro-3-(2-Chloro-Phenylcarbamoyl)Phenylboronic Acid is a sophisticated boronic acid derivative that serves as a critical building block in modern synthetic chemistry. This compound matters because it enables the precise construction of complex molecules through reliable cross-coupling reactions, such as the Suzuki-Miyaura reaction. Pharmaceutical, agrochemical, and advanced materials researchers need this high-purity intermediate to develop new active ingredients and functional polymers.

Application

  • Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly for targeted therapies.
  • Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and insecticides with specific modes of action.
  • Material Science: Building block for organic electronic materials, including OLEDs and conductive polymers.
  • Chemical Biology Probes: Utilized in the development of sensors and probes for biological research and diagnostics.
  • Ligand Synthesis: Serves as a precursor for creating specialized ligands used in catalysis.
  • Cross-Coupling Reactions: Essential reagent for Suzuki-Miyaura couplings to form biaryl and other carbon-carbon bonds.

Basic Information

Product Name 4-Fluoro-3-(2-Chloro-Phenylcarbamoyl)Phenylboronic Acid
CAS No. 1451393-31-9
Molecular Formula C13H10BClFNO3
Molecular Weight 293.49 g/mol
Synonyms 4-Fluoro-3-[(2-chlorophenyl)carbamoyl]benzeneboronic Acid; [4-Fluoro-3-[(2-chlorophenyl)carbamoyl]phenyl]boronic Acid; 2-Chloro-N-[2-fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoyl]aniline (Pinacol Ester); B-[4-Fluoro-3-[(2-chlorophenyl)carbamoyl]phenyl]boronic Acid; 1451393-31-9; 4-Fluoro-3-(2-chlorophenylcarbamoyl)phenylboronic acid
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Quality Control

Our 4-Fluoro-3-(2-Chloro-Phenylcarbamoyl)Phenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Assay (HPLC) ≥97.0%
Purity (HPLC, Area %) ≥98.0%
Water Content (KF) ≤0.5%
Residue on Ignition ≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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