Description

3-(3,5-Dichlorophenylcarbamoyl)-4-Fluorophenylboronic Acid is a high-purity, multi-functional boronic acid derivative designed for advanced organic synthesis. This compound is a critical building block in modern pharmaceutical and agrochemical research, enabling the formation of carbon-carbon bonds via Suzuki-Miyaura cross-coupling reactions. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel, complex molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the research and development of novel herbicides and fungicides, leveraging its halogenated aromatic structure for bioactivity.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of advanced polymeric materials, including sensors and organic electronic components.
• Chemical Biology Probes: Employed in the creation of boronic acid-based probes for detecting and studying biological processes such as carbohydrate recognition.
• Catalyst Ligand Development: Acts as a starting material for synthesizing novel ligands used in transition metal catalysis.
• Custom Synthesis & Contract Manufacturing: A vital component for custom synthesis houses serving the global life sciences market.

Basic Information

Item	Details
Product Name	3-(3,5-Dichlorophenylcarbamoyl)-4-Fluorophenylboronic Acid
CAS No.	1451393-28-4
Molecular Formula	C13H8BCl2FNO3
Molecular Weight	342.92 g/mol
Synonyms	4-Fluoro-3-((3,5-dichlorophenyl)carbamoyl)phenylboronic acid; (4-Fluoro-3-((3,5-dichlorophenyl)carbamoyl)phenyl)boronic acid; 3-Carbamoyl-4-fluorophenylboronic acid, 3,5-dichloro derivative; Boronic acid, B-[4-fluoro-3-[[(3,5-dichlorophenyl)amino]carbonyl]phenyl]-; 1451393-28-4; 3-(3,5-Dichlorophenylcarbamoyl)-4-fluorobenzeneboronic acid
EINECS	Contact for details

Quality Control

Every batch of 3-(3,5-Dichlorophenylcarbamoyl)-4-Fluorophenylboronic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data including HPLC purity, NMR, and mass spectrometry to ensure identity, potency, and consistency. Certificates of Analysis (COA) are available for all shipments, and our quality protocols are designed to meet the stringent requirements of cGMP and ICH guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (NMR)	Spectrum consistent with structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.