Description

3-Formyl-5-(Trifluoromethyl)Phenylboronic Acid is a high-value, multi-functional boronic acid derivative essential for modern synthetic chemistry. Its unique structure, featuring both a formyl group and a trifluoromethyl substituent on the aromatic ring, makes it a versatile and powerful building block for constructing complex molecular architectures. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing biaryl compounds with potential biological activity.
• Agrochemical Synthesis: Used to introduce the trifluoromethylphenyl moiety into novel herbicide and pesticide candidates, enhancing their lipophilicity and metabolic stability.
• Ligand & Catalyst Development: Serves as a starting material for creating sophisticated ligands used in asymmetric catalysis and transition metal complexes.
• Material Science: Employed in the synthesis of organic electronic materials, such as OLED (Organic Light-Emitting Diode) emitters and charge transport materials, where the boronic acid group enables precise molecular assembly.
• Chemical Biology & Proteomics: Can be utilized in the development of activity-based probes and affinity reagents due to its reactive aldehyde and boronic acid functional groups.
• Custom Synthesis & Contract Research: A critical reagent for custom synthesis organizations (CSOs) and R&D departments working on proprietary compound libraries and novel chemical entities.

Basic Information

Product Name	3-Formyl-5-(Trifluoromethyl)Phenylboronic Acid
CAS No.	1451393-24-0
Molecular Formula	C8H6BF3O3
Molecular Weight	217.94 g/mol
Synonyms	[5-(Trifluoromethyl)-3-formylphenyl]boronic acid; 3-Formyl-5-(trifluoromethyl)benzeneboronic acid; (3-Formyl-5-(trifluoromethyl)phenyl)boronic acid; Boronic acid, B-[3-formyl-5-(trifluoromethyl)phenyl]-; 5-Formyl-3-(trifluoromethyl)phenylboronic acid; 3-Carbaldehyde-5-(trifluoromethyl)phenylboronic acid
EINECS	Contact for details

Quality Control

Our 3-Formyl-5-(Trifluoromethyl)Phenylboronic Acid is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) with detailed specifications are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and may require storage under an inert atmosphere for long-term preservation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.