Description

3-Bromo-2-Chloro-6-Fluorophenylboronic Acid is a high-purity, multi-halogenated boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its value lies in enabling precise cross-coupling reactions, such as the Suzuki-Miyaura reaction, which are fundamental for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Material Science: Serves as a monomer or cross-linking agent in the production of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for exploring new synthetic pathways and creating compound libraries.
• Ligand Synthesis: Employed in the preparation of sophisticated ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	3-Bromo-2-Chloro-6-Fluorophenylboronic Acid
CAS No.	1451393-16-0
Molecular Formula	C6H4BBrClFO2
Molecular Weight	253.26 g/mol
Synonyms	(3-Bromo-2-chloro-6-fluorophenyl)boronic acid; 2-Chloro-3-bromo-6-fluorobenzeneboronic acid; Boronic acid, B-(3-bromo-2-chloro-6-fluorophenyl)-; 3-Bromo-2-chloro-6-fluorobenzeneboronic acid; B-(3-Bromo-2-chloro-6-fluorophenyl)boronic acid
EINECS	Contact for details

Quality Control

Our 3-Bromo-2-Chloro-6-Fluorophenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and elemental analysis, to ensure it meets the high-purity standards required for sensitive cross-coupling applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.