Description

4-Bromo-2-Fluoro-5-(Trifluoromethyl)Phenylboronic Acid is a high-value, multi-functional boronic acid derivative essential for modern synthetic chemistry. Its core value lies in serving as a versatile building block for constructing complex molecular architectures via cross-coupling reactions. This compound is critically needed by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used to create advanced active ingredients for crop protection products, leveraging the unique properties of the halogen and trifluoromethyl substituents.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands and organometallic catalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and semiconductors, where its structure aids in tuning electronic properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and target identification.
• Custom Synthesis and Contract Manufacturing: A critical raw material for CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client R&D pipelines.

Basic Information

Product Name	4-Bromo-2-Fluoro-5-(Trifluoromethyl)Phenylboronic Acid
CAS No.	1451393-15-9
Molecular Formula	C7H4BBrF4O2
Molecular Weight	286.82 g/mol
Synonyms	4-Bromo-2-fluoro-5-(trifluoromethyl)benzeneboronic acid; [4-Bromo-2-fluoro-5-(trifluoromethyl)phenyl]boronic acid; 2-Fluoro-4-bromo-5-(trifluoromethyl)phenylboronic acid; B-[4-Bromo-2-fluoro-5-(trifluoromethyl)phenyl]boronic acid; 4-Bromo-2-fluoro-α,α,α-trifluoro-m-tolylboronic acid; 1451393-15-9; Boronic acid, B-[4-bromo-2-fluoro-5-(trifluoromethyl)phenyl]-
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Fluoro-5-(Trifluoromethyl)Phenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every shipment. We support compliance with cGMP, ICH Q7, and REACH requirements for our global customer base.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light). Keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.