Description

3,5-Dichloro-2,6-Difluorophenylboronic Acid is a high-purity, multi-halogenated boronic acid derivative that serves as a critical building block in advanced organic synthesis. Its value lies in its unique substitution pattern, which enables precise cross-coupling reactions to construct complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries who require reliable, high-quality intermediates for drug discovery and specialty chemical production.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs), particularly in the development of complex heterocyclic compounds.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, where the difluoro-dichloro substitution pattern imparts specific biological activity and stability.
• Ligand & Catalyst Development: Serves as a starting material for synthesizing specialized ligands and organometallic catalysts used in asymmetric synthesis and polymerization processes.
• Materials Science Research: Employed in the synthesis of organic electronic materials, such as monomers for conductive polymers or components for organic light-emitting diodes (OLEDs).
• Chemical Biology Probes: Utilized to create tagged molecules and bioconjugates for studying biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and small-molecule libraries.

Basic Information

Product Name	3,5-Dichloro-2,6-Difluorophenylboronic Acid
CAS No.	1451393-11-5
Molecular Formula	C6H2BCl2F2O2
Molecular Weight	228.79 g/mol
Synonyms	(3,5-Dichloro-2,6-difluorophenyl)boronic acid; 2,6-Difluoro-3,5-dichlorophenylboronic acid; Boronic acid, B-(3,5-dichloro-2,6-difluorophenyl)-; 3,5-Dichloro-2,6-difluoro-benzeneboronic acid
EINECS	Contact for details

Quality Control

Our 3,5-Dichloro-2,6-Difluorophenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical parameters. Our quality commitment supports applications requiring high standards, including cGMP intermediates for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.