Description

2-Fluoro-3-Formyl-4-(Trifluoromethyl)Phenylboronic Acid is a high-value, multi-functional boronic acid derivative essential for modern synthetic chemistry. Its unique structure, featuring both a formyl and a trifluoromethyl group on a fluorinated phenyl ring, makes it a critical building block for constructing complex molecules. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used to construct advanced active ingredients for crop protection products, leveraging the stability imparted by the fluorine and trifluoromethyl groups.
• Material Science Research: Serves as a monomer or linker in the development of organic electronic materials, such as OLEDs and semiconductors.
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands for transition metal catalysis and organoboron chemistry.
• Chemical Biology Probes: Utilized to create tagged molecules for studying biological pathways and protein interactions.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs serving the global life sciences market.

Basic Information

Product Name	2-Fluoro-3-Formyl-4-(Trifluoromethyl)Phenylboronic Acid
CAS No.	1451393-07-9
Molecular Formula	C8H5BF4O3
Molecular Weight	235.93 g/mol
Synonyms	[2-Fluoro-3-formyl-4-(trifluoromethyl)phenyl]boronic acid; 2-Fluoro-3-formyl-4-(trifluoromethyl)benzeneboronic acid; (2-Fluoro-3-formyl-4-(trifluoromethyl)phenyl)boronic acid; Boronic acid, B-[2-fluoro-3-formyl-4-(trifluoromethyl)phenyl]-; 2-Fluoro-4-(trifluoromethyl)benzaldehyde-3-boronic acid; CAS 1451393-07-9
EINECS	Contact for details

Quality Control

Our 2-Fluoro-3-Formyl-4-(Trifluoromethyl)Phenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency suitable for demanding R&D and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.