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4-Bromo-2-Fluoro-3-Formylphenylboronic Acid CAS NO 1451393-06-8


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CAS No.:1451393-06-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

4-Bromo-2-Fluoro-3-Formylphenylboronic Acid is a sophisticated, multi-functional boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its unique structure, featuring bromo, fluoro, and formyl substituents on a phenylboronic acid core, makes it a highly versatile intermediate for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients through cross-coupling reactions like the Suzuki-Miyaura reaction.

Application

  • Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for targeted therapies.
  • Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with enhanced efficacy.
  • Material Science: Serves as a monomer or cross-linking agent in the creation of advanced polymers and organic electronic materials.
  • Ligand Synthesis: Employed for constructing complex ligands used in catalysis and metal-organic frameworks (MOFs).
  • Chemical Biology Probes: Utilized in the design of molecular probes and sensors for diagnostic applications.
  • Custom Synthesis: A valuable starting material for contract research organizations (CROs) and CDMOs performing bespoke synthetic routes.

Basic Information

Product Name 4-Bromo-2-Fluoro-3-Formylphenylboronic Acid
CAS No. 1451393-06-8
Molecular Formula C7H5BBrFO3
Molecular Weight 245.83 g/mol
Synonyms (4-Bromo-2-fluoro-3-formylphenyl)boronic acid; 3-Formyl-4-bromo-2-fluorophenylboronic acid; 4-Bromo-2-fluoro-3-formylbenzeneboronic acid; Boronic acid, B-(4-bromo-2-fluoro-3-formylphenyl)-; 1451393-06-8; 4-Bromo-2-fluoro-3-carboxaldehydephenylboronic acid
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Quality Control

Every batch of 4-Bromo-2-Fluoro-3-Formylphenylboronic Acid is produced and tested under a strict quality management system to ensure consistency and reliability for your critical applications. We employ advanced analytical techniques, including HPLC, NMR, and mass spectrometry, to verify identity, purity, and impurity profiles. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from incompatible materials.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Water Content (KF) ≤ 1.0%
Heavy Metals ≤ 20 ppm
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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