Description

3-Carboxy-2,4-Difluorophenylboronic Acid is a high-purity, multifunctional boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its value lies in the unique combination of a boronic acid group for Suzuki-Miyaura cross-coupling reactions and a carboxylic acid moiety for further derivatization, enabling the construction of complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active pharmaceutical ingredients (APIs) and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those containing difluorophenyl motifs for improved metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in creating advanced herbicides and fungicides where the difluoro and boronic acid functionalities contribute to target specificity and efficacy.
• Material Science: Serves as a monomer or cross-linking agent in the production of specialty polymers and organic electronic materials.
• Ligand for Catalysis: The boronic acid group can be utilized to form catalysts or catalyst supports for various organic transformations.
• Bioconjugation & Probe Development: The carboxylic acid allows for attachment to biomolecules, making it useful for creating diagnostic probes or bioconjugates.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D for exploring new synthetic pathways and creating compound libraries.

Basic Information

Item	Details
Product Name	3-Carboxy-2,4-Difluorophenylboronic Acid
CAS No.	1451393-05-7
Molecular Formula	C7H5BF2O4
Molecular Weight	201.92 g/mol
Synonyms	2,4-Difluoro-3-boronobenzoic Acid; (3-Carboxy-2,4-difluorophenyl)boronic Acid; 3-Borono-2,4-difluorobenzoic Acid; 2,4-Difluoro-3-carboxyphenylboronic Acid; Boronic acid, B-(3-carboxy-2,4-difluorophenyl)-; 1451393-05-7; Difluorophenylboronic acid carboxylic acid derivative
EINECS	Contact for details

Quality Control

Every batch of 3-Carboxy-2,4-Difluorophenylboronic Acid is produced under stringent quality management protocols to ensure consistency and reliability for your critical applications. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) in its original packaging to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.