Description

3-Bromo-5-Chloro-2,6-Difluorophenylboronic Acid is a high-purity, multi-halogenated phenylboronic acid derivative, a critical building block in modern synthetic chemistry. Its value lies in its unique substitution pattern, which enables precise cross-coupling reactions for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used to create advanced herbicides and fungicides with specific halogenated aromatic cores for enhanced efficacy.
• Material Science Research: Serves as a monomer or building block for developing organic electronic materials, such as OLEDs and semiconductors.
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands for transition metal catalysis.
• Chemical Biology Probes: Utilized to create tagged molecules for studying biological pathways and protein interactions.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis projects requiring specific halogenated boronic acids.

Basic Information

Product Name	3-Bromo-5-Chloro-2,6-Difluorophenylboronic Acid
CAS No.	1451393-03-5
Molecular Formula	C6H3BBrClF2O2
Molecular Weight	271.25 g/mol
Synonyms	(3-Bromo-5-chloro-2,6-difluorophenyl)boronic acid; 2,6-Difluoro-3-bromo-5-chlorophenylboronic acid; B-(3-Bromo-5-chloro-2,6-difluorophenyl)boronic acid; 3-Bromo-5-chloro-2,6-difluorobenzeneboronic acid; Boronic acid, B-(3-bromo-5-chloro-2,6-difluorophenyl)-; CAS 1451393-03-5
EINECS	Contact for details

Quality Control

Our 3-Bromo-5-Chloro-2,6-Difluorophenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and atmospheric exposure.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.