Description

3-Cyclopropyl-2,6-Difluorophenylboronic Acid is a high-purity organoboron compound serving as a versatile building block in advanced synthetic chemistry. Its value lies in enabling precise carbon-carbon bond formation, which is critical for constructing complex molecular architectures. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in central nervous system (CNS) and anti-infective research.
• Agrochemical Synthesis: Used to create advanced active ingredients for crop protection products, leveraging the cyclopropyl and difluoro motifs for enhanced biological activity and stability.
• Material Science Research: Employed in the development of organic electronic materials, such as ligands for OLEDs and other functional polymers.
• Chemical Biology Probes: Serves as a building block for creating labeled compounds and molecular probes used in diagnostic and biochemical research.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and libraries for high-throughput screening.

Basic Information

Product Name	3-Cyclopropyl-2,6-Difluorophenylboronic Acid
CAS No.	1451393-02-4
Molecular Formula	C9H9BF2O2
Molecular Weight	197.98 g/mol
Synonyms	(3-Cyclopropyl-2,6-difluorophenyl)boronic acid; 2,6-Difluoro-3-cyclopropylbenzeneboronic acid; B-(3-Cyclopropyl-2,6-difluorophenyl)boronic acid; 3-Cyclopropyl-2,6-difluorobenzeneboronic acid; Boronic acid, B-(3-cyclopropyl-2,6-difluorophenyl)-; 1451393-02-4; 3-Cyclopropyl-2,6-difluorophenyl-B(OH)2
EINECS	Contact for details

Quality Control

Our 3-Cyclopropyl-2,6-Difluorophenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency suitable for demanding synthetic applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.