Description

3-Bromo-6-Chloro-2-Fluorophenylboronicacid is a high-purity, multi-halogenated phenylboronic acid derivative, a crucial building block in modern synthetic chemistry. Its value lies in its unique substitution pattern, which enables precise cross-coupling reactions for constructing complex molecular architectures. This advanced intermediate is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used to construct complex heterocyclic scaffolds found in advanced herbicides, fungicides, and insecticides.
• Ligand & Catalyst Development: Serves as a starting material for creating specialized ligands and organometallic catalysts used in asymmetric synthesis.
• Materials Science Research: Employed in the synthesis of organic electronic materials, such as OLED (Organic Light-Emitting Diode) emitters and charge-transport molecules.
• Chemical Biology Probes: Utilized to build tagged molecules and bioconjugates for proteomics and diagnostic assay development.
• Custom Synthesis & Contract Manufacturing: A vital building block for custom synthesis houses serving the life sciences industry.

Basic Information

Item	Details
Product Name	3-Bromo-6-Chloro-2-Fluorophenylboronic acid
CAS No.	1451393-00-2
Molecular Formula	C6H4BBrClFO2
Molecular Weight	253.26 g/mol
Synonyms	(3-Bromo-6-chloro-2-fluorophenyl)boronic acid; 2-Fluoro-3-bromo-6-chlorophenylboronic acid; 3-Bromo-2-fluoro-6-chlorophenylboronic acid; Boronic acid, B-(3-bromo-6-chloro-2-fluorophenyl)-; 1451393-00-2; 3-Br-6-Cl-2-F-PhB(OH)2
EINECS	Contact for details

Quality Control

Our 3-Bromo-6-Chloro-2-Fluorophenylboronic acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high chemical purity and lot-to-lot consistency, meeting the stringent requirements for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.