Description

2-Chloro-6-Fluoro-3-Formylphenylboronic Acid is a high-purity, multifunctional boronic acid derivative essential for modern synthetic chemistry. Its core value lies in serving as a key building block for constructing complex molecular architectures via cross-coupling reactions. This compound is critically needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing biaryl compounds, which are core structures in many drug candidates.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, leveraging the halogen and formyl substituents for structural diversity.
• Material Science Research: Employed in the creation of organic electronic materials, ligands for catalysts, and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Serves as a building block for synthesizing molecular probes and sensors used in biochemical assays and diagnostic research.
• Process Chemistry & Scale-up: Supplied in consistent quality for process optimization and pilot-scale manufacturing of target molecules.
• Custom Synthesis & Contract Manufacturing: Provided to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	2-Chloro-6-Fluoro-3-Formylphenylboronic Acid
CAS No.	1451392-95-2
Molecular Formula	C7H5BClFO3
Molecular Weight	201.38 g/mol
Synonyms	(2-Chloro-6-fluoro-3-formylphenyl)boronic acid; 2-Chloro-6-fluorobenzaldehyde-3-boronic acid; 3-Borono-2-chloro-6-fluorobenzaldehyde; 2-Chloro-6-fluoro-3-carboxaldehydebenzeneboronic acid; Boronic acid, B-(2-chloro-6-fluoro-3-formylphenyl)-; 1451392-95-2
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-6-Fluoro-3-Formylphenylboronic Acid is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.