Description

3-Bromo-2-Fluoro-6-(Trifluoromethyl)Phenylboronic Acid is a high-purity, multi-functional boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the precise construction of complex molecular architectures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands and organometallic catalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as those for OLEDs and organic photovoltaics, due to its halogenated, electron-deficient aromatic system.
• Chemical Biology Probes: Utilized to create boronic acid-based sensors and probes for detecting biological analytes like sugars or peroxides.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs and fine chemical companies for custom synthesis projects requiring specific halogenated boronic acids.

Basic Information

Item	Details
Product Name	3-Bromo-2-Fluoro-6-(Trifluoromethyl)Phenylboronic Acid
CAS No.	1451392-89-4
Molecular Formula	C7H4BBrF4O2
Molecular Weight	286.82 g/mol
Synonyms	3-Bromo-2-fluoro-6-(trifluoromethyl)benzeneboronic acid; [3-Bromo-2-fluoro-6-(trifluoromethyl)phenyl]boronic acid; Boronic acid, B-[3-bromo-2-fluoro-6-(trifluoromethyl)phenyl]-; 2-Fluoro-3-bromo-6-(trifluoromethyl)phenylboronic acid; 3-Bromo-2-fluoro-alpha,alpha,α-trifluoro-o-tolylboronic acid; (3-Bromo-2-fluoro-6-(trifluoromethyl)phenyl)boronic acid
EINECS	Contact for details

Quality Control

Every batch of 3-Bromo-2-Fluoro-6-(Trifluoromethyl)Phenylboronic Acid is manufactured under strict quality management systems. We employ advanced analytical techniques, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing batch-specific results are provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.