Description

6-Bromo-3-Chloro-2-Fluorophenylboronic Acid is a high-purity, multi-halogenated boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its value lies in its unique halogen substitution pattern, which enables precise cross-coupling reactions for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active pharmaceutical ingredients (APIs) and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides with specific halogenated aromatic cores.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and semiconductors, where its halogen atoms fine-tune electronic properties.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands and organometallic catalysts used in asymmetric synthesis.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes and tags for studying biological pathways and protein interactions.
• Custom Synthesis and Contract Manufacturing: A vital raw material for CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	6-Bromo-3-Chloro-2-Fluorophenylboronic Acid
CAS No.	1451392-87-2
Molecular Formula	C6H4BBrClFO2
Molecular Weight	253.26 g/mol
Synonyms	(6-Bromo-3-chloro-2-fluorophenyl)boronic acid; 2-Fluoro-6-bromo-3-chlorophenylboronic acid; Boronic acid, B-(6-bromo-3-chloro-2-fluorophenyl)-; 1451392-87-2; 6-Bromo-3-chloro-2-fluorobenzeneboronic acid
EINECS	Contact for details

Quality Control

Our 6-Bromo-3-Chloro-2-Fluorophenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP standards where applicable to support our clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under an inert atmosphere when appropriate for prolonged use. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.