Description

2-Bromo-6-Fluoro-3-Hydroxyphenylboronic Acid is a high-value, multi-functional boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its unique halogenated and hydroxylated structure makes it an indispensable precursor for constructing complex molecules via cross-coupling reactions. This compound is primarily sought after by research scientists and process chemists in the pharmaceutical and agrochemical industries for the development of new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon in Suzuki-Miyaura cross-coupling reactions for the synthesis of novel drug candidates, particularly in oncology and CNS research.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, leveraging its halogenated aromatic core.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as OLEDs and conductive polymers.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and sensors for biochemical assays.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	2-Bromo-6-Fluoro-3-Hydroxyphenylboronic Acid
CAS No.	1451392-83-8
Molecular Formula	C6H5BBrFO3
Molecular Weight	234.82 g/mol
Synonyms	(2-Bromo-6-fluoro-3-hydroxyphenyl)boronic acid; 2-Bromo-6-fluoro-3-hydroxybenzeneboronic acid; 3-Borono-2-bromo-6-fluorophenol; Boronic acid, B-(2-bromo-6-fluoro-3-hydroxyphenyl)-; 1451392-83-8; 2-Br-6-F-3-OH-PhB(OH)2
EINECS	Contact for details

Quality Control

Our 2-Bromo-6-Fluoro-3-Hydroxyphenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.